Finding Ease in Perimenopause: Stories of ERr 731™ Across Cultures

Did you know that over 6 million women enter perimenopause every year?¹  

Of these women, around 80% can experience symptoms.²

When it comes to choosing how to support their wellbeing, each woman’s individual views on how they want to manage their perimenopausal symptoms can be different. This is because personal values and beliefs around hormonal healthcare are central to the choices women make for their bodies.³ 

To embrace the diverse experience of perimenopause, this article explores the stories of women from around the world who experienced benefits from using Siberian rhubarb (ERr 731™),⁴,⁶ a key ingredient found in Estrovera®. Used traditionally in many different cultures, herbal medicines such as ERr 731™ highlight how plant extracts can support perimenopausal women. 

Perimenopausal benefits ERr 731™: Women from South Asia  

Asian culture is renowned for its connection to traditional medicine, which often involves the use of plants to support balance within the body. Aligned with this approach, ERr 731™ helps to gently stimulate hormonal receptors within the body to offset the impact of reduced oestrogen levels in perimenopause.⁴ 

Highlight the benefits of ERr 731™ in South Asian women, one study reported a  20% improvement across several perimenopausal symptoms after 1 month.⁴ These women reported the following changes: 

• Hot flushes and sweating episodes improved by 21%  
• Sleep disturbances and unrefreshing sleep were improved by 14% 
• Feeling moody and irritable was lowered by 26%  
• Feeling mental and physical fatigue improved by 20% 
• Vaginal dryness was improved by 15% 
• Women’s experience of joint and muscle complaints was improved by 28% 

These women continued using ERr 731™, which delivered even better results when used for 3 months with a 68% improvement across multiple symptoms. 

• Hot flushes and sweating improved by 75% 
• Poor sleep was hugely improved by 70.3%  
• Irritable moods were reduced by 65% 
• Energy improved with a reduction in fatigue by 66% 
• Vaginal dryness continued to improve by 58% 
• Finally, point and muscle soreness was reduced by 68% 

These results highlight the potential for ERr 731™ to support these women within just four weeks. 

Perimenopause benefits ERr 731™: Women from Eastern Europe 

Research suggests that Eastern European women can experience mild symptoms but report higher scores for mood symptoms and hot flushes.⁵ Show to provide relief for these issues in women from Eastern Europe, a study conducted in Ukrainian women who used ERr 731™ demonstrated a -63% reduction after 3 months, and -83% reduction after 9 and 21 months 

These women reported the following changes after using ERr 731™ in common perimenopausal symptoms: 

• Hot flushes and night sweats improved across all time points by 66% 
• Poor sleep was better across all points by 68%  
• Irritability from 3, 9, and 21 months was reduced by 78%, 96% and 94% 
• Fatigue across all time points improved by 57%  
• Vaginal dryness across all 3 time points improved by 45%  
• Joint and muscle complaints across all time points were reduced by 50%  

Based on these stories, ERr 731™ offers a promising natural alternative for women experiencing perimenopausal symptoms. With its efficacy and safety having been demonstrated across diverse cultural backgrounds, ERr 731™ could be the natural solution you've been looking for. To learn more about this ingredient, check out this article here for more information.

Ease into Perimenopause Naturally

ERr 731™ is a well-tolerated extract shown to support women from different backgrounds to support the perimenopausal journey. In the spirit of providing accessible information for all women from all walks of life and backgrounds, the Jean Hailes Foundation for women’s health provides a range of resources in several languages, found here. For more specific information related to your perimenopause, we encourage you to reach out to a Healthcare Practitioner to learn more about the ways you can feel supported to embrace this next phase of wellness. 

References

1. OlaOlorun FM, Shen W. Menopause. Published: 19 Nov 2020. Accessed: March 14, 2025. from: https://oxfordre.com/publichealth/view/10.1093/acrefore/9780190632366.001.0001/acrefore-9780190632366-e-176  
2. Symptoms of Menopause. Jean Hailes. Updated Sept 4, 2023. Accessed March 25, 2025. https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms 
3. Williams M. Culturally responsive care for menopausal women. Maturitas. 2024;185:107995. doi:10.1016/j.maturitas.2024.107995 
4. Shah J, Chandanani S, Reddy J, et al. Evaluation of the efficacy and safety of Rheum rhaponticum root extract (ERr 731) for menopausal symptoms in perimenopausal Indian women: an interim analysis. J Mid-life Heal. 2021;12(2):108-115. doi:10.4103/jmh.jmh_86_21  
5. Bojar I, Lyubinets O, Novotny J, et al. Intensification of menopausal symptoms among female inhabitants of Eastern European countries. Ann Agric Environ Med. 2016;23(3):517-524. doi:10.5604/12321966.1219198 
6. Hasper I, Ventskovskiy BM, Rettenberger R, Heger PW, Riley DS, Kaszkin-Bettag M. Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. Menopause. 2009;16(1):117-131. doi:10.1097/gme.0b013e3181806446